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??: ???????     ??: 2020-06-05 05:07:03
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GlobaleffortaimstofinddiseasevectorsthatcanjumpfromanimalstohumansChinawillhelpleadaprojecttoidentifyunknownvirusesfromwildlifetobetterpreparehumansformajorepidemics?-?ifnotglobalpandemics.Theprojectistobelaunchedthisyear,accordingtooneofthecountry'stophealthofficials.TheGlobalViromeProjectwillstartinChinaandThailandwithfieldworktocollectsamplesfromwildanimalsandanalyzethevirusesdetected,saidGaoFu,headoftheChineseCenterforDiseaseControlandPrevention."Scientistswillcollectvirussamplesfromanimalssuchasbatsandratsforstudyusingtechniqueslikenextgeneration(DNA)sequencingtofindwhethernewvirusesexist,"hesaid.Theproject,estimatedtocostupto.2billion,isexpectedtotake10yearsandinvolvesmanycountriesincludingtheUnitedStates,BrazilandNigeria.Throughmoreintensiveandextensivestudyofvirusesfromanimalsthatcouldinfecthumans,itmaybepossibletodealwithvirusesusingpreemptivecontrolsandpreventioninsteadofpassive,reactivemeasures,Gaosaid."Weallknowtherearealmostcertainlynewvirusesthatcouldcausethenextglobalpandemic,butbasedontheexistingearlywarningcapacityfordiseases,wedonotknow,forexample,whichviruswillcauseanepidemic,"Gaosaid."Wearesurethatnewvirusstrainswillappearinthefuturealongwithchangesinourecology,environmentandhumanbehaviors."Forinstance,humans'abuseofantibioticshasleadtothepotentialdevelopmentofsuperbugs."Therearemanyviruseslivinginwildanimals,sowecanidentifyvirusesandthoroughlystudythosethatcouldpasstohumans,"Gaosaid."Ideallywecandevelopvaccinesandadiagnosisforsuchvirusesevenbeforetheycausehumanepidemics."Itisknownthat263virusescaninfecthumans,butscientistsestimatetheremaybemorethanhalfamillionvirusesthatliveinbirdsandmammalsandthatareunknowntohumansthatmaybecapableofinfectinghumans,andtheyaretheprimarysubjectoftheproject'sresearch,Gaosaid.Evenifalargenumberofsuchunknownvirusesareidentified,itispossiblethatjustasmallfractionofthemhavetheabilitytocausemajorepidemicsthatcausehumandeaths,hesaid.However,consideringthehugecostofamajorepidemiclikeSARStohumanhealthandeconomies,thefindingsoftheprojectstillhavethepotentialtogreatlyreducelossesthroughimprovedearlydiagnosisandidentificationofhostsvulnerabletoanewvirusafteranoutbreak,accordingtoGao.AsimilarprojectcarriedoutbytheUSAgencyforInternationalDevelopmentprovedthefeasibilityoftheGlobalViromeProjectandprovideshelpfulexperience,hesaid.TheUSAIDproject,knownasPredictandlaunchedin2009,withChinaaparticipant,ledtofindingsofmorethan1,000virusespreviouslyunknowntohumans.Theprojectcostwasover0million,hesaid.SomeofthetechnologiesusedforthatprojecthaveprovedreliableandeconomicallyaffordableandcanbeusedfortheGlobalViromeProject,Gaosaid.? ?? ?Technologycompaniesdominatedthisyear'sFortune500listreleasedonMonday,withApple,Amazon,Alphabet,Microsoft,andIBM,amongothers,allinthetop50.Appledroppedfromlastyear'sNo.3tothefourthplacedespitea6percentgaininannualsales,butitledthewayinprofitswithmorethan48billionU.S.dollarsinnetincome,accordingtothelist.Amazoncrackedthetop10forthefirsttime,continuingitsremarkablegrowthrun:Saleshavejumpedsome70billiondollarsintwoyears.Amazon'senormitystemsfromitsroleasthelargestU.S.digitalretailer,thefastest-growingpartofthemarket.Sharesofthecompanyrose0.35percenttotradeat1,579.91dollarsapieceinearlytradingonMonday.Apple,Alphabet,Microsoft,andAmazonwerethetopfourinmarketvalueasofMarch29thisyear,accordingtothelist.TheyarefollowedbyBerkshireHathaway,Facebook,andJPMorganChase.Fortunerankstheworld'stopcompaniesbyrevenueeachyearand2018marksthe64thrunningofthelist.Thisyear'sFortune500companiesrepresenttwo-thirdsoftheU.S.GDPwith12.8trilliondollarsinrevenues,1.0trilliondollarsinprofits,21.6trilliondollarsinmarketvalue,andemploy28.2millionpeopleworldwide.Walmart,ExxonMobil,BerkshireHathaway,Apple,UnitedHealthGroup,McKesson,CVSHealth,Amazon,ATT,andGeneralMotorsmadethetop10thisyear.Amongthem,ExxonMobilandGeneralMotorshavebeenonthelisteveryyearsinceitstartedin1955.? ?? ?


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